1.W. Chen, J. Wu, L. Li, Z. Zhang, J. Ren, Y. Liang, F. Chen, C. Yang, Z. Zhou, S.S. Su, X. Zheng, Z. Zhang, C.Q. Zhong, H. Wan, M. Xiao, X. Lin, X.H. Feng, and J. Han（韩家淮）*. Ppm1b negatively regulates necroptosis through dephosphorylating Rip3. Nat Cell Biol. 17:434-444 (2015).

2.L. Li, Y. Liu, H.Z. Chen, F.W. Li, J.F. Wu, H.K. Zhang, J.P. He, Y.Z. Xing, Y. Chen, W.J. Wang, X.Y. Tian, A.Z. Li, Q. Zhang, P.Q. Huang, J. Han, T. Lin（林天伟）*, and Q. Wu（吴乔）*. Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation. Nat Chem Biol. 11:339-346 (2015).

3.Z. Huang, S.Q. Wu, Y. Liang*, X. Zhou, W. Chen, L. Li, J. Wu, Q. Zhuang, C. Chen, J. Li, C.Q. Zhong, W. Xia, R. Zhou, C. Zheng, and J. Han（韩家淮）*. RIP1/RIP3 binding to HSV-1 ICP6 initiates necroptosis to restrict virus propagation in mice. Cell host & microbe. 17:229-242 (2015).

4.W. Xie, L. Zhang, H. Jiao, L. Guan, J. Zha, X. Li, M. Wu, Z. Wang, J. Han, and H. You（尤涵）*. Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA. Autophagy. 11:1623-1635 (2015).

5.H. Wu, L. Wei, F. Fan, S. Ji, S. Zhang, J. Geng, L. Hong, X. Fan, Q. Chen, J. Tian, M. Jiang, X. Sun, C. Jin, Z.Y. Yin, Q. Liu, J. Zhang, F. Qin, K.H. Lin, J.S. Yu, X. Deng, H.R. Wang, B. Zhao, R.L. Johnson, L. Chen（陈兰芬）*, and D. Zhou（周大旺）*. Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis. Nature communications. 6:6239 (2015).

6.Y. Li, S. Wu, S. Xiong, and G. Ouyang（欧阳高亮）*. Deficiency of periostin protects mice against methionine-choline-deficient diet-induced non-alcoholic steatohepatitis. J Hepatol. 62:495-497 (2015).

7.Y. Xu, H. Ma, J. Shao, J. Wu, L. Zhou, Z. Zhang, Y. Wang, Z. Huang, J. Ren, S. Liu, X. Chen, and J. Han（韩家淮）*. A Role for Tubular Necroptosis in Cisplatin-Induced AKI. J Am Soc Nephrol(2015).

8.M.C. Cai, Q. Xu, Y.J. Pan, W. Pan, N. Ji, Y.B. Li, H.J. Jin, K. Liu, and Z.L. Ji（纪志梁）*. ADReCS: an ontology database for aiding standardization and hierarchical classification of adverse drug reaction terms. Nucleic Acids Res. 43:D907-913 (2015).

9.T. Yoshikawa, J. Wu, M. Otsuka, T*. Kishikawa, M. Ohno, C. Shibata, A. Takata, F. Han, Y.J. Kang, C.Y. Chen, A.B. Shyu, J. Han（韩家淮）*, and K. Koike. ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression. Nucleic Acids Res. 43:7577-7589 (2015).

10.P. Mo, Q. Zhou, L. Guan, Y. Wang, W. Wang, M. Miao, Z. Tong, M. Li, S. Majaz, Y. Liu, G. Su, J. Xu, and C. Yu（俞春东）*. Amplified in breast cancer 1 promotes colorectal cancer progression through enhancing notch signaling. Oncogene. 34:3935-3945 (2015). （IF:   8.459）

11.H. Jiao, G.Q. Su, W. Dong, L. Zhang, W. Xie, L.M. Yao, P. Chen, Z.X. Wang, Y.C. Liou, and H. You（尤涵）*. Chaperone-like protein p32 regulates ULK1 stability and autophagy. Cell Death Differ(2015).

12.Y. Chen, R. Wu, H.Z. Chen, Q. Xiao, W.J. Wang, J.P. He, X.X. Li, X.W. Yu, L. Li, P. Wang, X.C. Wan, X.H. Tian, S.J. Li, X. Yu, and Q. Wu（吴乔）*. Enhancement of Hypothalamic STAT3 Acetylation by Nuclear Receptor Nur77 Dictates Leptin Sensitivity. Diabetes. 64:2069-2081 (2015).

13.M. Liu, Y. Li, and R. Chen（陈瑞川）*. CaMKII: do not work too hard in the failing heart. J Pathol. 235:669-671 (2015).

14.Y. Cui, S. Rao, B. Chang, X. Wang, K. Zhang, X. Hou, X. Zhu, H. Wu, Z. Tian, Z. Zhao, C. Yang, and T. Huang（黄涛）*. AtLa1 protein initiates IRES-dependent translation of WUSCHEL mRNA and regulates the stem cell homeostasis of Arabidopsis in response to environmental hazards. Plant, cell & environment(2015).

15.W.J. Wang, Y. Wang, P.P. Hou, F.W. Li, B. Zhou, H.Z. Chen, X.L. Bian, Q.X. Cai, Y.Z. Xing, J.P. He, H. Zhang, P.Q. Huang, T. Lin, and Q. Wu（吴乔）*. Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity. Chem Biol. 22:1040-1051 (2015).

16.H. Qiu, X. Fang, Q. Luo*, and G. Ouyang（欧阳高亮）*. Cancer stem cells: a potential target for cancer therapy. Cell Mol Life Sci(2015).

17.Y. Lin, A.Y. Liu, C. Fan, H. Zheng, Y. Li, C. Zhang, S. Wu, D. Yu, Z. Huang, F. Liu, Q. Luo, C.J. Yang, and G. Ouyang（欧阳高亮）*. MicroRNA-33b Inhibits Breast Cancer Metastasis by Targeting HMGA2, SALL4 and Twist1. Sci Rep. 5:9995 (2015).

18.W. Zheng, L. Qiu, R. Wang, X. Feng, Y. Han, Y. Zhu, D. Chen, Y. Liu, L. Jin（金利华）*, and Y. Li（李勇）*. Selective targeting of PPARgamma by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency. Sci Rep. 5:12222 (2015).

19.C. Chen（陈灿和）*, F. Tian, L. Lu, Y. Wang, Z. Xiao, C. Yu, and X. Yu（余娴文）*. Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction. J Cell Sci. 128:3290-3303 (2015).