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S. Zhang, Q. Chen, Q. Liu, Y. Li, X. Sun, L. Hong, S. Ji, C. Liu, J. Geng, W. Zhang, Z. Lu, Z.Y. Yin, Y. Zeng, K.H. Lin, Q. Wu, Q. Li, K. Nakayama, K.I. Nakayama, X. Deng, R.L. Johnson, L. Zhu, D. Gao, L. Chen*, and D. Zhou*. Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2. Cancer cell. 31:669-684 e667 (2017).（IF：27.407）

J. Geng, S. Yu, H. Zhao, X. Sun, X. Li, P. Wang, X. Xiong, L. Hong, C. Xie, J. Gao, Y. Shi, J. Peng, R.L. Johnson, N. Xiao, L. Lu, J. Han, D. Zhou*, and L. Chen*. The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells. Nature immunology. 18:800-812 (2017).（IF：21.506）

T. Yoshikawa, J. Wu, M. Otsuka*, T. Kishikawa, N. Suzuki, A. Takata, M. Ohno, R. Ishibashi, M. Yamagami, R. Nakagawa, N. Kato, M. Miyazawa, J. Han*, and K. Koike. Repression of MicroRNA Function Mediates Inflammation-associated Colon Tumorigenesis. Gastroenterology. 152:631-643 (2017).（IF：18.392）

W.Y. Cai*, L.Y. Lin, H. Hao, S.M. Zhang, F. Ma, X.X. Hong, H. Zhang, Q.F. Liu, G.D. Ye, G.B. Sun, Y.J. Liu, S.N. Li, Y.Y. Xie, J.C. Cai*, and B.A. Li*. Yes-associated protein/TEA domain family member and hepatocyte nuclear factor 4-alpha (HNF4alpha) repress reciprocally to regulate hepatocarcinogenesis in rats and mice. Hepatology. 65:1206-1221 (2017).（IF：13.246）

L. Zhang, M. Cai, Z. Gong, B. Zhang, Y. Li, L. Guan, X. Hou, Q. Li, G. Liu, Z. Xue, M.H. Yang, J. Ye, Y.E. Chin, and H. You*. Geminin facilitates FoxO3 deacetylation to promote breast cancer cell metastasis. The Journal of clinical investigation. 127:2159-2175 (2017).（IF：12.784）

S.C. Nair, R. Xu, S. Pattaradilokrat, J. Wu, Y. Qi, M. Zilversmit, S. Ganesan, V. Nagarajan, R.T. Eastman, M.S. Orandle, J.C. Tan, T.G. Myers, S. Liu, C.A. Long, J. Li*, and X.Z. Su*. A Plasmodium yoelii HECT-like E3 ubiquitin ligase regulates parasite growth and virulence. Nature communications. 8:223 (2017).（IF：12.124）

X.L. Bian, H.Z. Chen, P.B. Yang, Y.P. Li, F.N. Zhang, J.Y. Zhang, W.J. Wang, W.X. Zhao, S. Zhang, Q.T. Chen, Y. Zheng, X.Y. Sun, X.M. Wang, K.Y. Chien, and Q. Wu*. Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation. Nature communications. 8:14420 (2017).（IF：12.124）

Y. Zhang, S.S. Su, S. Zhao, Z. Yang, C.Q. Zhong, X. Chen, Q. Cai, Z.H. Yang, D. Huang, R. Wu, and J. Han*. RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome. Nature communications. 8:14329 (2017).（IF：12.124）

J. Zhang, S. Wang, B. Jiang, L. Huang, Z. Ji, X. Li, H. Zhou, A. Han, A. Chen, Y. Wu, H. Ma, W. Zhao, Q. Zhao, C. Xie, X. Sun, Y. Zhou, H. Huang, M. Suleman, F. Lin, L. Zhou, F. Tian, M. Jin, Y. Cai, N. Zhang, and Q. Li*. c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis. Nature communications. 8:13732 (2017).（IF：12.124）

Jiang Hua, He Hongbin, Chen Yun, Huang Wei, Cheng Jinbo, Ye Jin, Wang Aoli, Tao Jinhui, Wang Chao, Liu Qingsong, Jin Tengchuan, Jiang Wei*, Deng Xianming*, Zhou Rongbin*. Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders. Journal of Experimental Medicine. 2017, 214(11):3219-3238.   （IF: 11.991）

Z. Ma, X. Zhao, J. Huang, X. Jia, M. Deng, D. Cui, Z. Du, G. Fu*, G. Ouyang*, and C. Xiao*. A critical role of periostin in B-cell acute lymphoblastic leukemia. Leukemia. 31:1835-1837 (2017).（IF：11.705）

H. Ran, S. Kong, S. Zhang, J. Cheng, C. Zhou, B. He, Q. Xin, J.P. Lydon, F.J. DeMayo, G.S. Feng, G. Xia, Z. Lu*, C. Wang*, and H. Wang*. Nuclear Shp2 directs normal embryo implantation via facilitating the ERalpha tyrosine phosphorylation by the Src kinase. Proceedings of the National Academy of Sciences of the United States of America. 114:4816-4821 (2017).（IF：9.661）

G. Li, X. Liu, C. Xing, H. Zhang, S.M. Shimeld*, and Y. Wang*. Cerberus-Nodal-Lefty-Pitx signaling cascade controls left-right asymmetry in amphioxus. Proceedings of the National Academy of Sciences of the United States of America. 114:3684-3689 (2017).（IF：9.661）

J. Jiang, F. Gui, Z. He, L. Li, Y. Li, S. Li, X. Wu, Z. Deng, X. Sun, X. Huang, W. Huang, S. Han, T. Zhang, Z. Wang, B. Jiao, S. Song, H. Wang, L. Chen, D. Zhou, Q. Liu, R. Ren*, J. Zhang*, and X. Deng*. Targeting BRK-Positive Breast Cancers with Small-Molecule Kinase Inhibitors. Cancer research. 77:175-186 (2017).（IF：9.122）

Du, W. Tian, M. Wei, W. Yan, H. He, D. Zhou, X. Huang, S. Li, and X. Ouyang*. The DTH8-Hd1 Module Mediates Day-Length-Dependent Regulation of Rice Flowering. Molecular plant. 10:948-961 (2017).（IF：8.827）

Z. Yang, B. Jiang, Y. Wang, H. Ni, J. Zhang, J. Xia, M. Shi, L.M. Hung, J. Ruan, T.W. Mak, Q. Li*, and J. Han*. 2-HG Inhibits Necroptosis by Stimulating DNMT1-Dependent Hypermethylation of the RIP3 Promoter. Cell reports. 19:1846-1857 (2017).（IF：8.282）

B. Jiang, J. Zhang, J. Xia, W. Zhao, Y. Wu, M. Shi, L. Luo, H. Zhou, A. Chen, H. Ma, Q. Zhao, M. Suleman, F. Lin, L. Zhou, J. Wang, Y. Zhang, Y. He, X. Li, L.M. Hung, T.W. Mak, and Q. Li*. IDH1 Mutation Promotes Tumorigenesis by Inhibiting JNK Activation and Apoptosis Induced by Serum Starvation. Cell reports. 19:389-400 (2017).（IF：8.282）

W. Wan, K. Peng, M. Li, L. Qin, Z. Tong, J. Yan, B. Shen, and C. Yu*. Histone demethylase JMJD1A promotes urinary bladder cancer progression by enhancing glycolysis through coactivation of hypoxia inducible factor 1alpha. Oncogene. 36:3868-3877 (2017).（IF：7.519）

B. Cai, J. Wu, X. Yu,X.Z. Su*, and R.F. Wang*. FOSL1 Inhibits Type I Interferon Responses to Malaria and Viral Infections by Blocking TBK1 and TRAF3/TRIF Interactions. mBio. 8:(2017).（IF：6.956）

Zhang C Li Z Cui H Jiang Y Yang Z Wang X Gao H Liu C Zhang S Su XZ* Yuan J*.. Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite Development. MBio. 2017, 8(6).（IF：6.956）

Y. Ge, F. Yan, M. Zourelidou, M. Wang, K. Ljung, A. Fastner, U.Z. Hammes, M. Di Donato, M. Geisler, C. Schwechheimer, and Y. Tao*. SHADE AVOIDANCE 4 Is Required for Proper Auxin Distribution in the Hypocotyl. Plant physiology. 173:788-800 (2017).（IF：6.456）

Yan Zhenwei, Liu Xin, Ljung Karin, Li Shuning, Zhao Wanying, Yang Fan, Wang Meiling, Tao Yi*. Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1. Plant Physiology. 2017, 175(3):1438-1454.（IF：6.456）

G.L. Huang, W. Zhang, H.Y. Ren, P. Zhou, Y. Chen, Q.X. Chen*, and D.Y. Shen*. Oncogenic retinoic acid receptor alpha promotes human colorectal cancer growth through simultaneously regulating p21 transcription and GSK3beta/beta-catenin signaling. Cancer letters. 388:118-129 (2017).（IF：6.375）

H.Y. Jin, H. Oda, P. Chen, C. Yang, X. Zhou, S.G. Kang, E. Valentine, J.M. Kefauver, L. Liao, Y. Zhang, A. Gonzalez-Martin, J. Shepherd, G.J. Morgan, T.S. Mondala, S.R. Head, P.H. Kim, N. Xiao, G. Fu, W.H. Liu, J. Han, J.R. Williamson, and C. Xiao*. Differential Sensitivity of Target Genes to Translational Repression by miR-17~92. PLoS genetics. 13:e1006623 (2017).（IF：6.1）

B. Li, J. Guo, Z. Xi, J. Xu, Z. Zuo, and C. Wang*. Tributyltin in male mice disrupts glucose homeostasis as well as recovery after exposure: mechanism analysis. Archives of toxicology. 91:3261-3269 (2017).（IF：5.901）

J. Ren, X. Jia, Y. Zhao, W. Shi, J. Lu, Y. Zhang, J. Wu, B. Liang, R. Wu, G. Fu, and J. Han*. The RIP3-RIP1-NF-kappaB signaling axis is dispensable for necroptotic cells to elicit cross-priming of CD8+ T cells. Cellular & molecular immunology. 14:639-642 (2017).（IF：5.897）

Hu Guangwei, Li Guang, Wang Hui, Wang Yiquan*. Hedgehog participates in the establishment of left-right asymmetry during amphioxus development by controlling Cerberus expression. Development. 2017, 144(24):4694-4703.   (IF: 5.843)

Cui Dan, Huang Zhengjie, Liu Yingfu, Ouyang Gaoliang*. The multifaceted role of periostin in priming the tumor microenvironments for tumor progression. Cellular and Molecular Life Sciences. 2017, 74(23):4287-4291.   (IF：5.788)

W. Cai, G. Chen, Q. Luo, J. Liu, X. Guo, T. Zhang, F. Ma, L. Yuan, B. Li*, and J. Cai*. PMP22 Regulates Self-Renewal and Chemoresistance of Gastric Cancer Cells. Molecular cancer therapeutics. 16:1187-1198 (2017).（IF：5.764）

Cheng Jianghong, Zhong Yanhong, Chen Shuai, Sun Yan, Huang Lantang, Kang Yujia, Chen Baozhen, Chen Gang, Wang Fengli, Tian Yingpu, Liu Wenjie, Feng Gen-Sheng, Lu Zhongxian*. Gab2 mediates hepatocellular carcinogenesis by integrating multiple signaling pathways. FASEB Journal. 2017, 31(12):5530.   （IF: 5.498）

J.X. Zhao, Y.W. Yuan, C.F. Cai, D.Y. Shen, M.L. Chen, F. Ye, Y.J. Mi, Q.C. Luo, W.Y. Cai, W. Zhang, Y. Long, Y. Zeng, G.D. Ye*, and S.Y. Yang*. Aldose reductase interacts with AKT1 to augment hepatic AKT/mTOR signaling and promote hepatocarcinogenesis. Oncotarget. 8:66987-67000 (2017).（IF：5.168）

J.X. Zhao, L.R. Liu, X.Y. Yang, F. Liu*, and Z.G. Zhang*. Serum CA19-9 as a marker of circulating tumor cells in first reflux blood of colorectal cancer patients. Oncotarget. 8:67918-67932 (2017).（IF：5.168）

H. Peng, H. Jin, H. Zhuo*, and H. Huang*. Enhanced antitumor efficacy of cisplatin for treating ovarian cancer in vitro and in vivo via transferrin binding. Oncotarget. 8:45597-45611 (2017).（IF：5.168）

R.S. Wu, J.J. Hong, J.F. Wu, S. Yan, D. Wu, N. Liu, Q.F. Liu, Q.W. Wu, Y.Y. Xie, Y.J. Liu, Z.Z. Zheng, E.C. Chan*, Z.M. Zhang*, and B.A. Li*. OVOL2 antagonizes TGF-beta signaling to regulate epithelial to mesenchymal transition during mammary tumor metastasis. Oncotarget. 8:39401-39416 (2017).（IF：5.168）