Recent Events
1. G.D. Ye, G.B. Sun, P. Jiao, C. Chen, Q.F. Liu, X.L. Huang, R. Zhang, W.Y. Cai, S.N. Li, J.F. Wu, Y.J. Liu, R.S. Wu, Y.Y. Xie, E.C. Chan, Y.C. Liou, and B.A. Li*. OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors. Gastroenterology. 150:659-671 e616 (2016). (IF: 18.187)
2. C.S. Zhangand S.C. Lin*. AMPK Promotes Autophagy by Facilitating Mitochondrial Fission. Cell metabolism. 23:399-401 (2016). (IF: 17.303)
3. C.S. Zhang, M. Li, T. Ma, Y. Zong, J. Cui, J.W. Feng, Y.Q. Wu, S.Y. Lin, and S.C. Lin*. Metformin Activates AMPK through the Lysosomal Pathway. Cell metabolism. 24:521-522 (2016). (IF: 17.303)
4. F. Fan, Z. He, L.L. Kong, Q. Chen, Q. Yuan, S. Zhang, J. Ye, H. Liu, X. Sun, J. Geng, L. Yuan, L. Hong, C. Xiao, W. Zhang, X. Sun, Y. Li, P. Wang, L. Huang, X. Wu, Z. Ji, Q. Wu, N.S. Xia, N.S. Gray, L. Chen, C.H. Yun, X. Deng*, and D. Zhou*. Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration. Science translational medicine. 8:352ra108 (2016). (IF: 16.264)
5. X. Chen, W.T. He, L. Hu, J. Li, Y. Fang, X. Wang, X. Xu, Z. Wang, K. Huang, and J. Han*. Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis. Cell research. 26:1007-1020 (2016). (IF: 14.812)
6. Y. Zhangand J. Han*. Electrophysiologist shows a cation channel function of MLKL. Cell research. 26:643-644 (2016). (IF: 14.812)
7. T.Y. Li, Y. Sun, Y. Liang, Q. Liu, Y. Shi, C.S. Zhang, C. Zhang, L. Song, P. Zhang, X. Zhang, X. Li, T. Chen, H.Y. Huang, X. He, Y. Wang, Y.Q. Wu, S. Chen, M. Jiang, C. Chen, C. Xie, J.Y. Yang, Y. Lin, S. Zhao, Z. Ye, S.Y. Lin, D.T. Chiu, and S.C. Lin*. ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy. Molecular cell. 62:359-370 (2016). (IF: 13.958)
8. L. Guan, L. Zhang, Z. Gong, X. Hou, Y. Xu, X. Feng, H. Wang, and H. You*. FoxO3 inactivation promotes human cholangiocarcinoma tumorigenesis and chemoresistance through Keap1-Nrf2 signaling. Hepatology. 63:1914-1927 (2016). (IF: 11.711)
9. W.H. Liu*, S.G. Kang, Z. Huang, C.J. Wu, H.Y. Jin, C.J. Maine, Y. Liu, J. Shepherd, M. Sabouri-Ghomi, A. Gonzalez-Martin, S. Xu, A. Hoffmann, Y. Zheng, L.F. Lu, N. Xiao, G. Fu*, and C. Xiao*. A miR-155-Peli1-c-Rel pathway controls the generation and function of T follicular helper cells. The Journal of experimental medicine. 213:1901-1919 (2016). (IF: 11.24)
10. X. Lu, X. Zhu, Y. Li, M. Liu, B. Yu, Y. Wang, M. Rao, H. Yang, K. Zhou, Y. Wang, Y. Chen, M. Chen, S. Zhuang, L.F. Chen*, R. Liu*, and R. Chen*. Multiple P-TEFbs cooperatively regulate the release of promoter-proximally paused RNA polymerase II. Nucleic acids research. 44:6853-6867 (2016). (IF: 9.202)
11. Y. Zhang, C. Wen, S. Liu, L. Zheng, B. Shen, and Y. Tao*. Shade avoidance 6 encodes an Arabidopsis flap endonuclease required for maintenance of genome integrity and development. Nucleic acids research. 44:1271-1284 (2016). (IF: 9.202)
12. Z. Li, Q. Hao, J. Luo, J. Xiong, S. Zhang, T. Wang, L. Bai, W. Wang, M. Chen, W. Wang, L. Gu, K. Lv, and J. Chen*. USP4 inhibits p53 and NF-kappaB through deubiquitinating and stabilizing HDAC2. Oncogene. 35:2902-2912 (2016). (IF: 7.932)
13. Z. Wang, S. Xiong, Y. Mao, M. Chen, X. Ma, X. Zhou, Z. Ma, F. Liu, Z. Huang, Q. Luo, and G. Ouyang*. Periostin promotes immunosuppressive premetastatic niche formation to facilitate breast tumour metastasis. The Journal of pathology. 239:484-495 (2016). (IF: 7.381)
14. Qian, CZ; Mao, WW; Liu, Y; Ren, H; Lau, OS; Ouyang, XH; Huang, X*. Dual-Source Nuclear Monomers of UV-B Light Receptor Direct Photomorphogenesis in Arabidopsis. Molecular Plant. 9:1671-1674 (2016). (IF: 7.142)
15.S. Chen, Y. Kang, Y. Sun, Y. Zhong, Y. Li, L. Deng, J. Tao, Y. Li, Y. Tian, Y. Zhao, J. Cheng, W. Liu, G.S. Feng, and Z. Lu*. Deletion of Gab2 in mice protects against hepatic steatosis and steatohepatitis: a novel therapeutic target for fatty liver disease. Journal of molecular cell biology. 8:492-504 (2016). (IF: 6.459)
16. H. Ma, J.S. Pan*, L.X. Jin, J. Wu, Y.D. Ren, P. Chen, C. Xiao*, and J. Han*. MicroRNA-17~92 inhibits colorectal cancer progression by targeting angiogenesis. Cancer letters. 376:293-302 (2016). (IF: 5.992)
17. J. Hou, T. Wang, Q. Xie, W. Deng, J.Y. Yang, S.Q. Zhang*, and J.C. Cai*. N-Myc-interacting protein (NMI) negatively regulates epithelial-mesenchymal transition by inhibiting the acetylation of NF-kappaB/p65. Cancer letters. 376:22-33 (2016). (IF: 5.992)
18. Ou, ZM; Sun, YX; Lin, L; You, NC; Liu, X; Li, HC; Ma, YC; Cao, L; Han, Y; Liu, M; Deng, YQ; Yao, LM; Lu, QR; Chen, Y*. Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination. Journal of Neuroscience.36:10560-10573. (IF: 5.924)
19. X.M. Zhao, Z. Chen, J.B. Zhao, P.P. Zhang, Y.F. Pu, S.H. Jiang, J.J. Hou, Y.M. Cui, X.L. Jia, and S.Q. Zhang*. Hsp90 modulates the stability of MLKL and is required for TNF-induced necroptosis. Cell death & disease. 7:e2089 (2016). (IF: 5.378)
20. Y. Qin, J. Pan, M. Cai, L. Yao, and Z. Ji*. Pattern Genes Suggest Functional Connectivity of Organs. Scientific reports. 6:26501 (2016). (IF: 5.228)
21. L. Huang, Z. Xi, C. Wang, Y. Zhang, Z. Yang, S. Zhang, Y. Chen, and Z. Zuo*. Phenanthrene exposure induces cardiac hypertrophy via reducing miR-133a expression by DNA methylation. Scientific reports. 6:20105 (2016). (IF: 5.228)
22. C. Wu, L. Zhang, P. Li, Q. Cai, X. Peng, K. Yin, X. Chen, H. Ren, S. Zhong, Y. Weng, Y. Guan, S. Chen, J. Wu*, J. Li*, and T. Lin*. Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71. Biochimica et biophysica acta. 1860:1299-1307 (2016). (IF: 5.083)
23. Q. Liu, Z. Cheng, L. Luo, Y. Yang, Z. Zhang, H. Ma, T. Chen, X. Huang, S.Y. Lin, M. Jin, Q. Li*, and X. Li*. C-terminus of MUC16 activates Wnt signaling pathway through its interaction with beta-catenin to promote tumorigenesis and metastasis. Oncotarget. 7:36800-36813 (2016). (IF: 5.008)
24. M. Li, W. Wang, Y. Dan, Z. Tong, W. Chen, L. Qin, K. Liu, W. Li, P. Mo*, and C. Yu*. Downregulation of amplified in breast cancer 1 contributes to the anti-tumor effects of sorafenib on human hepatocellular carcinoma. Oncotarget. 7:29605-29619 (2016). (IF: 5.008)
25. C. Fan, Y. Lin, Y. Mao, Z. Huang, A.Y. Liu, H. Ma, D. Yu, A. Maitikabili, H. Xiao, C. Zhang, F. Liu, Q. Luo, and G. Ouyang*. MicroRNA-543 suppresses colorectal cancer growth and metastasis by targeting KRAS, MTA1 and HMGA2. Oncotarget. 7:21825-21839 (2016). (IF: 5.008)
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